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Research Bites

Preview PepsiCo nutrition science publications at a glance

An encompassing review of meta-analyses and systematic reviews of the effect of oats on all-cause mortality, cardiovascular risk, diabetes risk, body weight/adiposity and gut health

 

Key Topics Covered
  • Encompassing Review
  • Comprehensive search of systematic reviews and meta-analyses
  • Explored effect of oats on all-cause mortality, cardiovascular risk, diabetes risk, body weight/adiposity, and gut health

Change in liking following the reduction in sweetness level of carbonated beverages: A randomized controlled parallel trial

 

Key Topics Covered
  • Clinical Intervention Study
  • Randomized, double-blind, controlled, parallel design
  • Study aimed to investigate whether different methods of reducing sweetness coming from sugar or low-calorie sweeteners could change sweetness preference and perceived intensity in US and Mexican adults

Chia seeds (Salvia hispanica L.), incorporated into cookies, reduce postprandial glycaemic variability but have little or no effect on subjective appetite

 

Key Topics Covered
  • Clinical Intervention Study
  • A controlled feeding experiment using a randomized, double-blind, cross-over design
  • Study aimed to determine the lowest effective dose of chia seeds that can elicit satiety & glucose control as compared to the control

Trends and patterns of chickpea consumption among United States adults: Analyses of National Health and Nutrition Examination Survey Data

 

Key Topics Covered
  • Epidemiology and Population Health Study
  • Data from National Health and Nutrition Examination Survey (NHANES) 2003-2018
  • Explored trends and sociodemographic patterns among chickpea consumers

Estimated sweetness in US diet among children and adults declined from 2001 to 2018: A serial cross-sectional surveillance study using NHANES 2001–2018

 

Key Topics Covered
  • Epidemiology and Population Health Study
  • 24-h dietary recall data of the National Health and Nutrition Examination Survey (NHANES)
  • Evaluated trends in the sweetness (caloric or low-calorie sweetened) of the diet in US children and adults

Narrative review on the effects of oat and sprouted oat components on blood pressure

 

Key Topics Covered
  • Narrative Review
  • Comprehensive search of systemic reviews, meta-analyses, and clinical intervention studies
  • Explored oats and sprouted oat components and blood pressure

Oats lower age-related systemic chronic inflammation (iAge) in adults at risk for cardiovascular disease

 

Key Topics Covered
  • Clinical Intervention Study
  • A randomized, double-blind, placebo-controlled, parallel arm design clinical trial
  • Researched the relationship between oats and systematic chronic inflammation

The inhibition of intestinal glucose absorption by oat-derived avenanthramides

 

Key Topics Covered
  • In Vitro Study
  • Cell models used to investigate the effect of the oat derived phenolic, avenanthramide, on intestinal glucose transporters
  • Tested the relationship between glucose uptake and the presence of avenanthramides

The importance of molecular weight in determining the minimum dose of oat β-glucan required to reduce the glycemic response in healthy subjects without diabetes: A systematic review and meta-regression analysis

 

Key Topics Covered
  • Systematic Review/Meta-Analysis
  • Linear associations assessed by random effect meta-regressions
  • Aimed to determine minimum amount of β-glucan required to reduce glycemic response

Balanced hybrid nutrient density score compared to Nutri-Score and Health Star Rating using receiver operating characteristic curve analyses

 

Key Topics Covered
  • Methodology study describing score development and validation
  • The bHNDS is a new nutrient density score that aligns with the latest Dietary Guidelines for Americans and can be used to identify nutrient dense foods/beverages
  • Compared the performance of a new nutrient profiling model to two established models

Resiliency of the digestive system during aging and the impact of diet

 

 

Key Topics Covered
  • Narrative Review/White Paper
  • Comprehensive search of reviews
  • Explored physiological changes in digestive system with aging and impact of diet on these changes

Effect of oat β-glucan on affective and physical feeling states in healthy adults: Evidence for reduced headache, fatigue, anxiety and limb/joint pains

 

Key Topics Covered
  • Clinical Intervention Study
  • Randomized, double-blind, placebo-controlled, parallel arm design
  • Aimed to assess the effect of oat β-glucan on non-gastrointestinal symptoms in humans

In vitro–in vivo validation of stimulatory effect of oat ingredients on Lactobacilli

 

Key Topics Covered
  • Clinical Intervention Study
  • Oat products tested in vitro and a randomized, single-blind, placebo-controlled, cross-over human study
  • Explored oat ingredients effect on probiotics in the human gastrointestinal tract

A systematic review and meta-analysis of randomized controlled trials on the effects of oats and oat processing on postprandial blood glucose and insulin responses

 

Key Topics Covered
  • Systematic Review/Meta-Analysis
  • Review conducted in accordance with the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)
  • Investigated effects of oats and oat processing on glycemic responses

The role of oat nutrients in the immune system: A narrative review

 

Key Topics Covered
  • Narrative Review
  • Discussed the relationship between oat nutrients and immune system response to infections

The effect of cereal β-glucan on body weight and adiposity: A review of efficacy and mechanism of action

 

Key Topics Covered
  • Systematic Review/Meta-Analysis
  • Four observational and 72 human intervention studies reviewed
  • Examined the relationship between β-glucan and body weight and adiposity

The prebiotic effects of oats on blood lipids, gut microbiota, and short-chain fatty acids in mildly hypercholesterolemic subjects compared with rice: A randomized, controlled trial
 

Key Topics Covered
  • Clinical Intervention Study 
  • Randomized, controlled trial
  • Explored the effects of oat consumption on cholesterol and the gut microbiota

Increasing oat β-glucan viscosity in a breakfast meal slows gastric emptying and reduces glycemic and insulinemic responses but has no effect on appetite, food intake, or plasma ghrelin and PYY responses in healthy humans
 

Key Topics Covered
  • Clinical Intervention Study
  • Randomized, placebo-controlled, crossover trial
  • Aimed to determine the effect of β-glucan viscosity alteration on the primary endpoint of food intake
     

Impact of oat processing on glycemic and insulinemic responses in healthy humans: A randomized clinical trial

 

Key Topics Covered
  • Clinical Intervention Study
  • Randomized, crossover trial
  • Explored the effect of oat processing on glycemic and insulinemic responses