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El equipo de Health & Nutrition Sciences de PepsiCo (H&NS) estudia los efectos de la nutrición en el cuerpo humano, así como a los diversos ingredientes utilizados en nuestros productos y su contribución a la salud y el bienestar. Invertimos en investigación que continúa mostrando los beneficios que puede ofrecer el portafolio actual. Esta investigación contribuye al cuerpo más amplio de evidencia dentro de la ciencia de la nutrición para contribuir en el conocimiento dentro del campo.

Estos esfuerzos de investigación también se utilizan para ampliar los conocimientos de los profesionales y de la comunidad científica de la nutrición, para hacer recomendaciones de nutrición basadas en evidencia.  Esto se logra a nivel mundial mediante la asociación con instituciones académicas, por contratos con organizaciones de investigación y asociaciones comerciales, sobre la base de hipótesis claramente establecidas y su correspondiente análisis. 

Los estudios utilizan los métodos de investigación validados como apropiados “estándar de oro”,  mismos que se monitorean para garantizar que se sigan los principios que subyacen a los estándares de buenas prácticas clínicas.

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La revisión sistemática resume la literatura científica actual que se ajusta a los criterios de elegibilidad predeterminados para responder a una pregunta científica particular / El metaanálisis utiliza métodos estadísticos para analizar los resultados de múltiples estudios científicos.

2021

  • Trends in vitamin C consumption in the United States: 1999–2018

    Brauchla, M., Dekker, M. J., & Rehm, C. D. (2021). Trends in vitamin C consumption in the United States: 1999–2018. Nutrients, 13(2), 420. doi:10.3390/nu13020420

     

    Abstract:

    Low intakes of fruits and vegetables have resulted in suboptimal intakes of several micronutrients, including vitamin C. This cross-sectional study used data from 84,902 children/adults (≥1 y) who completed a 24-h dietary recall as part of the United States National Health and Nutrition Examination Survey (1999–2018). Mean vitamin C intakes from foods/beverages were calculated as were trends in major food/beverage sources of vitamin C. Percentages below the Estimated Average Requirement (EAR) were estimated. Overall, mean vitamin C consumption declined by 23% (97–75 mg/d; p-value for trend < 0.001). 100% fruit juice was the leading source of vitamin C (25.6% of total or 21.7mg/d), but this declined by 48% (25–13 mg/d; p-value for trend < 0.001). Whole fruit increased among children/adolescents (+75.8%;10–17 mg/d; p-value for trend < 0.001), but not adults, while the vegetable contribution was generally unchanged. The proportion of the population below the EAR increased by 23.8% on a relative scale or 9 percentage points on an absolute scale (38.3–47.4%). Declines in vitamin C intake is driven largely by decreases in fruit juice coupled with modest increases in whole fruit. Due to associations between vitamin C intake and numerous health outcomes these trends warrant careful monitoring moving forward.

  • Understanding whole grain awareness and consumption in select Indian cohorts

    Madan, J., Hussain, N., Joshi, S., Mehra, J., . . . Thomas, J. (2021). Understanding whole grain awareness and consumption in select Indian cohorts. Journal Indian Medical Association, 119(1), 88-94.

     

    Abstract:

    Background and Introduction: Grains are an integral part of Indian diet. Carbohydrates constitute to 60-70% of total daily calorie intake and grains are the key carbohydrate source. Including whole grains(WG) in the diet for its health benefits is recommended in dietary guidance around the world. There is consistent evidence to support existence of barriers to WG consumption in Indian population but limited evidence assessing their level of awareness and knowledge on WG. Thus, an independent survey was designed for assessing the level of awareness and consumption of WG amongst millennials and nutritionist and dieticians. Data collection and analysis: Tool employed was self-developed questionnaire. SPSS software and MS Excel were used for analysing data. Results: Only 2% of the surveyed millennials were aware of all aspects of WG. Nutritionists and dieticians showed better responses than millennials. Daily WG consumption in millennials was less than 10% (42 g/day) compared to total grain consumption (432g/day) across food categories. 50% nutritionists and dieticians consume oats for breakfast. Conclusion: Results highlight the importance of raising awareness on the knowledge and consumption of WG amongst urban Indian millennials. It also emphasises the need of national recommendations, encouraging consumers to make half of their total grain consumption as WG. A WG stamp from FSSAI for identification of products with considerable amount of WG and campaigns with public-private partnership supported by nutritionist, dietitians, culinary experts can further help in attaining the goal of a WG rich “Sustainable Healthy Diet” for a healthy living

  • Yogurt fortified with vitamins and probiotics impacts the frequency of upper respiratory tract infections but not gut microbiome: A multicenter double-blind placebo controlled randomized study

    Odintsova, V., Klimenko, N., Tyakht, A., Volokh, O., . . . Berezhnaya, Y. (2021). Yogurt fortified with vitamins and probiotics impacts the frequency of upper respiratory tract infections but not gut microbiome: A multicenter double-blind placebo controlled randomized study. Journal of Functional Foods, 83, 104572. doi:10.1016/j.jff.2021.104572

     

    Abstract:

    Probiotics and vitamins can impact immune responses and modulate gut microbiome. We evaluated the effects of consuming a yogurt fortified with vitamins and probiotic Lacticaseibacillus casei and rhamnosus on upper respiratory tract infections frequency and gut microbiome during a 3-month intervention. The study included 2 case groups (consuming different flavours) and a placebo group of healthy adults (n = 158–160 in each group). The effects on URTI-related parameters in both case groups were gender-specific. The female subjects had lower URTI incidence and frequency, while for the males no significant differences were found. The URTI duration was shorter in one of the probiotic groups for females and in both such groups - for males. The observed changes in microbiome composition, blood and stool parameters were not different from those observed in the placebo group. Consumption of fortified fermented dairy foods is promising for improving immunity status within the general population.

2020

  • A randomized, crossover study of the acute cognitive and cerebral blood flow effects of phenolic, nitrate and botanical beverages in young, healthy humans

    Jackson, P. A., Wightman, E. L., Veasey, R., Forster, J., . . . Kennedy, D. O. (2020). A randomized, crossover study of the acute cognitive and cerebral blood flow effects of phenolic, nitrate and botanical beverages in young, healthy humans. Nutrients, 12(8), 1-16. doi:10.3390/nu12082254

     

    Abstract:

    Background: In whole foods, polyphenols exist alongside a wide array of other potentially bioactive phytochemicals. Yet, investigations of the effects of combinations of polyphenols with other phytochemicals are limited. Objective: The current study investigated the effects of combining extracts of beetroot, ginseng and sage with phenolic-rich apple, blueberry and coffee berry extracts. Design: This randomized, double-blind, placebo-controlled crossover design investigated three active beverages in 32 healthy adults aged 18–49 years. Each investigational beverage comprised extracts of beetroot, ginseng and sage. Each also contained a phenolic-rich extract derived from apple (containing 234 mg flavanols), blueberry (300 mg anthocyanins) or coffee berry (440 mg chlorogenic acid). Cognition, mood and CBF parameters were assessed at baseline and then again at 60, 180 and 360 min post-drink. Results: Robust effects on mood and CBF were seen for the apple and coffee berry beverages, with increased subjective energetic arousal and hemodynamic responses being observed. Fewer effects were seen with the blueberry extract beverage. Conclusions: Either the combination of beetroot, ginseng and sage was enhanced by the synergistic addition of the apple and coffee berry extract (and to a lesser extent the blueberry extract) or the former two phenolic-rich extracts were capable of evincing the robust mood and CBF effects alone.

  • A snack formulated with ingredients to slow carbohydrate digestion and absorption reduces the glycemic response in humans: A randomized controlled trial

    Rebello, C. J., Johnson, W. D., Pan, Y., Larrivee, S., . . . Greenway, F. L. (2020). A snack formulated with ingredients to slow carbohydrate digestion and absorption reduces the glycemic response in humans: A randomized controlled trial. Journal of Medicinal Food, 23(1), 21-28. doi:10.1089/jmf.2019.0097

     

    Abstract:

    This study compared the effect of a snack with ingredients to slow carbohydrate digestion (Test-snack) on postprandial blood glucose and insulin concentrations and subjective appetite ratings. We hypothesized that Test-snack would lower glucose and insulin responses and reduce appetite compared with a Control-snack. Overweight or obese subjects (n=17) completed a randomized crossover study. Glucose, insulin, and appetite ratings were measured before consuming each snack or white bread (Bread) and over a period of 4h. Subjects received Test-snack, Control-snack, or Bread in random order at least a week apart. The a priori primary outcome was the glucose response, and the secondary outcomes were appetite ratings and insulin responses. Mixed effects statistical models were used to perform analysis of variance in terms of the area under curve (AUC) and at specific time points. The 2-h AUC for glucose was significantly lower with Test-snack compared to Control-snack and Bread (AUC and 95% confidence intervals: Test=2186.43 [1783.36–2589.51]; Control=3293.75 [2893.97–3693.54]; Bread=2800.28 [2405.79–3194.77] mg/dL · min). Four-hour AUC for glucose, and insulin, followed a similar pattern except that Test-snack did not differ from Bread. The glucose concentrations peaked at 45min under all three conditions, but Test-snack elicited a lower response than Control-snack and Bread (P<.01). Test increased fullness and satisfaction and reduced hunger and prospective intake compared to Bread (P<.02), but was not significantly different from Control-snack. Ingredients that slow carbohydrate digestion in a snack reduce the postprandial glucose and insulin responses compared to a product without these ingredients.

  • Association of whole-grain and dietary fiber intake with cardiometabolic risk in children and adolescents

    Fulgoni, V. L., Brauchla, M., Fleige, L., & Chu, Y. (2020). Association of whole-grain and dietary fiber intake with cardiometabolic risk in children and adolescents. Nutrition and Health, 26(3), 243-251. doi:10.1177/0260106020928664

     

    Abstract:

    Background: Diet is known to affect many risk factors of cardiovascular disease (CVD), a leading cause of mortality and morbidity. Aim: The objective of this study was to explore the potential association between whole grain and dietary fiber with CVD risk factors, including metabolic syndrome (MetS) in children and adolescents using National Health and Nutrition Examination Survey (NHANES) 2003–2014. Methods: Two days of 24-hour recall data from 16,507 children and adolescents age 2–18 years were used to estimate dietary intakes. Continuous MetS scores (cMetS) were computed by aggregating age/sex regressed z-scores of waist circumference, mean arterial blood pressure, high-density lipoprotein-cholesterol, triglycerides, and glucose. Regression analyses were used to assess association of fiber and whole grain intake with cardiometabolic markers including MetS after adjusting for demographic factors. Results: Increasing tertiles of fiber intake were significantly associated with 3% lowered risk MetS in adolescents age 13–18 years. Additionally, increasing intake tertiles of fiber were associated with reduced risk elevated cholesterol (5–11% reduction), elevated diastolic blood pressure (10–23% reduction) in adolescents age 13–18 years, and risk of obesity (3–5% reduction) in children and adolescent age 2–18 years. Increasing tertiles of whole grain intake were only associated with reduced risk of elevated triglycerides (52% risk reduction) in adolescents age 13–18 years. Conclusion: The results suggest that intake of dietary fiber was inversely associated with several markers of cardiovascular disease risk including MetS.

  • Avenanthramide supplementation reduces eccentric exercise-induced inflammation in young men and women

    Zhang, T., Zhao, T., Zhang, Y., Liu, T., . . . Ji, L. L. (2020). Avenanthramide supplementation reduces eccentric exercise-induced inflammation in young men and women. Journal of the International Society of Sports Nutrition, 17, 41. doi:10.1186/s12970-020-00368-3

     

    Abstract:

    Background: Avenanthramides (AVA) are a group of di-phenolic acids found only in oats and have shown antioxidant and anti-inflammatory effects in vitro and in vivo. Eccentric muscle contraction is intimately involved in rigorous exercise that activates systemic and local inflammatory responses. The objective of the study is to evaluate whether chronic AVA supplementation could attenuate peripheral inflammatory and immunological markers in human subjects in response to an acute bout of downhill running (DR). Methods: Eleven male and thirteen female subjects voluntarily participated in this double-blinded, randomized controlled study and were randomly divided into AVA-supplemented (AVA) or control (C) groups. All subjects conducted a DR protocol at −10% grade with an intensity equivalent to 75% of their maximal heart rate. Blood samples were collected at rest and various time points (0-72h) after DR (PRE). After an 8-week washout period, participants received two cookies daily containing either 206mg/kg (AVA) or 0mg/kg (C) AVA for 8weeks. Following the oat supplementation regimen, the DR and blood sampling protocols were repeated (POST). Plasma inflammatory and immunological markers were measured using Multiplex immunoassay and muscle soreness was evaluated with pain rating scale. Results: DR increased plasma creatine kinase (CK) activity (P<0.01) during PRE, but the response was reduced at 24 and 48h during POST vs. PRE regardless of AVA status (P<0.05). Neutrophil respiratory burst (NRB) levels were elevated at 4 and 24h (P<0.05) during PRE but were significantly decreased at 0–48h during POST vs. PRE (P<0.05 or 0.01). Granulocyte-colony stimulating factor (G-CSF), the neutrophil stimulating cytokine, was also increased in response to DR but showed lower levels in AVA compared to C during POST vs. PRE (P<0.05). Plasma interleukin-6 (IL-6) content showed an increase at 0 and 4h during PRE and 0h during POST (P<0.01), whereas during POST there was a trend toward a lower IL-6 level in AVA vs. C (P=0.082). Plasma levels of anti-inflammatory agent interleukin-1 receptor antagonist (IL-1Ra) showed an increase at 4h during PRE, and was significantly elevated in AVA vs. C during POST. Both soluble vascular cell adhesion molecule-1 (sVCAM-1) and monocyte chemoattractant protein-1 (MCP-1) contents increased at 0 and 24h post DR during PRE as well as POST sessions, however, sVCAM-1 content was lower in AVA vs. C during POST (P<0.05) and MCP-1 levels were below resting level at 24, 48 and 72h during POST (P<0.05). DR increased muscle pain at all post-DR time points (P<0.01), but the pain level was alleviated by oat supplementation at 48 and 72h during POST regardless of AVA treatment (P<0.05). Conclusions: Oat AVA supplementation reduced circulatory inflammatory cytokines and inhibited expression of chemokines and cell adhesion molecules induced by DR.

  • Contribution of 100% fruit juice to micronutrient intakes in the United States, United Kingdom and Brazil

    Mitchell, E. S., Musa-Veloso, K., Fallah, S., Lee, H. Y., . . . Gibson, S. (2020). Contribution of 100% fruit juice to micronutrient intakes in the United States, United Kingdom and Brazil. Nutrients, 12(5), 1258. doi:10.3390/nu12051258

     

    Abstract:

    The contribution of 100% fruit juice (FJ) to the total daily intakes of energy, sugars, and select vitamins and minerals and to the recommended dietary allowances (RDAs) or adequate intake (AI) of these micronutrients was assessed in individuals reporting the consumption of 100% FJ in the national dietary intake surveys of the United States (U.S.; n = 8661), the United Kingdom (UK; n = 2546) and Brazil (n = 34,003). Associations of 100% FJ intake with the odds of being overweight or obese also were assessed. Data from the U.S. National Health and Nutrition Examination Survey (2013–2014), the UK National Diet and Nutrition Survey (2012–2014), and Brazil’s Pesquisa de Orçamentos Familiares (2008–2009) were used, and all analyses were limited to individuals reporting consumption of 100% FJ on at least one day of the dietary intake survey. Approximately 34%, 37%, and 42% of individuals surveyed reported the consumption of 100% FJ on at least one day of the dietary intake survey in the U.S., UK, and Brazil, respectively, and the average daily intakes of 100% FJ were 184 g, 130 g, and 249 g, respectively. Across the 3 countries, 100% FJ contributed to 3–6% of total energy intakes, 12–31% of total sugar intakes, 21–54% of total vitamin C intakes, 1–12% of total vitamin A intakes, 4–15% of total folate intakes, 7–17% of total potassium intakes, 2–7% of total calcium intakes, and 4–12% of total magnesium intakes. In a multivariate logistic regression model, juice intake was associated with a significant reduction in the odds of being overweight or obese in UK adults (OR = 0.79; 0.63, 0.99), and significant increases in the odds of being overweight or obese in UK children (OR = 1.16; 1.01, 1.33) and Brazilian adults (OR = 1.04; 1.00, 1.09). Nutrient contributions of 100% FJ vary according to regional intake levels. In all three countries studied, 100% FJ contributed to more than 5% of the RDAs for vitamin C and folate. In the U.S. and Brazil, 100% FJ contributed to more than 5% of the RDA for magnesium and more than 5% of the AI for potassium.

  • Daily eating frequency in US adults: Associations with low-calorie sweeteners, body mass index, and nutrient intake (NHANES 2007–2016)

    Hunt, K. J., St. Peter, J. V., Malek, A. M., Vrana-Diaz, C., . . . Greenberg, D. (2020). Daily eating frequency in US adults: Associations with low-calorie sweeteners, body mass index, and nutrient intake (NHANES 2007–2016). Nutrients, 12(9), 1-16. doi:10.3390/nu12092566

     

    Abstract:

    Studies of relationships between eating frequency and/or timing and energy intake have not examined associations with low-calorie sweeteners (LCS). We assessed the frequency of eating behavior related to LCS consumption emphasizing timing, calorie intake, and body mass index (BMI) among United States (US) adults aged ≥19 years. Using the National Health and Nutrition Examination Survey (NHANES) 2007–2016, we defined eating episodes as food and/or beverage intake within 15 min of one another over the first 24-h dietary recall. We coded items ingested during episodes (n = 136,938) and assessed LCS presence using US Department of Agriculture (USDA) food files. Episode analysis found intakes of foods only (27.4%), beverages only (29.5%), and foods with beverages (43.0%). LCS items were consumed without concurrent calories from other sources in fewer than 2.7% of all episodes. Within participants having normal weight (29.4%), overweight (33.6%) and obese (37.1%) BMIs, LCS consumers (35.2% overall) evidenced: more episodes/day; and fewer: calories, carbohydrates, fats, and protein per episode. Per person, those consuming LCS had lower total calories and higher fiber intake per day. LCS consumption was associated with higher BMI. Number of eating episodes/day and longer hours when eating episodes occurred were also consistently associated with higher BMI. Consuming LCS did not modify these relationships. These results did not show that LCS consumption was associated with increased caloric intake from other dietary sources.

  • Emerging science on whole grain intake and inflammation

    Sang S., Idehen E., Zhao Y., & Chu Y. (2020). Emerging science on whole grain intake and inflammation. Nutrition Reviews, 71(S1), 21-28. doi: 10.1093/nutrit/nuz079

     

    Abstract:

    Although the biological mechanisms surrounding the widely reported association between whole grain (WG) consumption and reduced risk of several diseases are not fully understood, there is growing evidence suggesting that inflammation may be an essential mediator in this multifaceted process. It also appears that several mechanisms influence the modulatory actions of WGs on inflammation, including the effect of fiber, phytochemicals, and their microbial-derived metabolites. While some of these effects are direct, others involve gut microbiota, which transform important bioactive substances into more useful metabolites that moderate inflammatory signaling pathways. This review evaluates emerging evidence of the relationship between WGs and their effects on markers of subclinical inflammation, and highlights the role of fiber, unique WG phytochemicals, and gut microbiota on the anti-inflammatory effects of WG intake.

  • Foreword: Overview of symposium on whole grains, dietary fiber, and public health

    Chu Y. F., Wang S., Liu F., Mathews R., & Chen J. (2020). Foreword: Overview of symposium on whole grains, dietary fiber, and public health. Nutrition Reviews, 78(S1), 1-5. doi:10.1093/nutrit/nuz066

  • Frequency of fruit juice consumption and association with nutrient intakes among Canadians

    Murphy, M. M., Barraj, L. M., Brisbois, T. D., & Duncan, A. M. (2020). Frequency of fruit juice consumption and association with nutrient intakes among Canadians. Nutrition and Health, 26(4), 277-283. doi:10.1177/0260106020944299

     

    Abstract:

    Background: In Canada, studies on consumption of 100% fruit juice and nutrient intakes are limited. Aim: This study aimed to evaluate nutrient intakes and adequacy of intake by frequency of fruit juice consumption. Methods: Individuals ≥1 year (n = 34,351) participating in the Canadian Community Health Survey, 2004 with a 24-hour dietary recall and reported usual frequency of fruit juice consumption (assumed to be 100% juice) were categorized by frequency of consumption as <0.5, ≥0.5 to <1.5, or ≥1.5 times/day. Results: More frequent consumption of fruit juice (≥0.5 times/day) was associated with higher intakes of total fruits and vegetables, whole fruits, energy, total sugars, vitamin C and potassium. More frequent consumption of fruit juice was associated with improved intake adequacy of vitamin C for adults. Conclusions: Fruit juice consumption contributes to increased intakes of vitamin C and potassium as well as energy and total sugars, thus presenting a trade-off for consumers to balance.

  • Global review of heart health claims for oat β-glucan products

    Mathews, R., Kamil, A., & Chu, Y. (2020). Global review of heart health claims for oat β-glucan products. Nutrition Reviews, 78(S1), 78-97. doi:10.1093/nutrit/nuz069

     

    Abstract:

    Coronary heart disease (CHD) is the leading cause of death globally. Consumption of whole grains and cereal fiber, as part of a healthy diet, can lower the risk of CHD. Health claims on food products are effective in helping consumers select healthful diets. The US Food and Drug Administration was the first to approve a health claim, in 1997, between β-glucan soluble fiber from whole oats, oat bran, and whole oat flour and reduced risk of CHD. Only a few countries have approved similar claims. Since 1997, a significant amount of additional evidence has been published on the relationship between oat β-glucan and CHD. To assist other jurisdictions in potentially utilizing this claim, the full extent of data that supports this claim (ie, the evidence utilized by the US Food and Drug Administration to substantiate the claim, as well as the results of 49 clinical trials published since 1997) are reviewed here. The complexities involved in authoring evidence-based health claims, including the impact of processing on β-glucan cholesterol-lowering efficacy in approving eligible β-glucan products, are also discussed.

  • Global review of whole grain definitions and health claims

    Mathews, R., & Chu, Y. (2020). Global review of whole grain definitions and health claims. Nutrition Reviews, 78(S1), 98-106. doi:10.1093/nutrit/nuz055

     

    Abstract:

    Recommendations to increase whole grain consumption are part of dietary guidelines around the world. To assist consumers in meeting this recommendation, some countries, and health-promoting organizations, have defined qualifying criteria for a whole grain food for product labeling or health claims. Other countries have not yet developed similar guidelines. Existing whole grain definitions and health claims are reviewed here. While there appears to be increasing consensus for defining a whole grain, significant disparity exists in defining a whole grain food when a product is not 100% whole grain. Moreover, while whole grain health claims have been approved in a few countries, other countries have concluded there is insufficient evidence to substantiate such claims.

  • Increasing oat β-glucan viscosity in a breakfast meal slows gastric emptying and reduces glycemic and insulinemic responses but has no effect on appetite, food intake, or plasma ghrelin and PYY responses in healthy humans

    Wolever, T. M. S., Tosh, S. M., Spruill, S. E., Jenkins, A. L., . . . Steinert, R. E. (2020). Increasing oat β-glucan viscosity in a breakfast meal slows gastric emptying and reduces glycemic and insulinemic responses but has no effect on appetite, food intake, or plasma ghrelin and PYY responses in healthy humans: A randomized, placebo-controlled, crossover trial. American Journal of Clinical Nutrition, 111(2), 319-328. doi:10.1093/ajcn/nqz285

     

    Abstract:

    Background: The viscosity of oat β-glucan (OBG) determines its effect on serum cholesterol and glycemic responses, but whether OBG viscosity affects gastric emptying, appetite, and ad libitum food intake is unknown. Objectives: We aimed to determine the effect of altering the amount or molecular weight (MW) and, hence, viscosity of OBG in a breakfast meal on the primary endpoint of food intake at a subsequent meal. Methods: Overnight-fasted males (n = 16) and nonpregnant females (n = 12) without diabetes, aged 18–60 y, with BMI 20.0–30.0 kg/m² who were unrestrained eaters participated in a double-blind, randomized, crossover study at a contract research organization. Participants consumed, in random order, breakfast meals equivalent in weight, energy, and macronutrients consisting of white-bread, butter, jam, and 2% milk plus hot cereal [Cream of Rice (CR), or instant-oatmeal plus either 3 g oat-bran (2gOBG), 10 g oat-bran (4gOBG), or 10 g oat-bran plus β-glucanase (4gloMW) to reduce OBG MW and viscosity compared with 4gOBG]. Gastric emptying, subjective appetite, and glucose, insulin, ghrelin, and peptide tyrosine tyrosine (PYY) responses were assessed for 3 h and then subjects were offered an ad libitum lunch (water and pizza). Results: Pizza intakes (n = 28) after CR, 2gOBG, 4gOBG, and 4gloMW (mean ± SEM: 887 ± 64, 831 ± 61, 834 ± 78, and 847 ± 68 kcal, respectively) were similar (nonsignificant). Compared with CR, 4gOBG significantly reduced glucose (78 ± 10 compared with 135 ± 15 mmol × min/L) and insulin (14.0 ± 1.6 compared with 26.8 ± 3.5 nmol × min/L) incremental area-under-the-curve and delayed gastric-emptying half-time (geometric mean: 285; 95% CI: 184, 442, compared with geometric mean: 105; 95% CI: 95, 117 min), effects not seen after 4gloMW. Subjective appetite, PYY, and ghrelin responses after 2gOBG, 4gOBG, and 4gloMW were similar to those after CR. Conclusions: The results demonstrate that OBG viscosity determines its effect on postprandial glucose, insulin, and gastric emptying. However, we were unable to demonstrate a significant effect of OBG on appetite or food intake, regardless of its viscosity.

  • Moderate acute malnutrition prevention with a ready-to-use supplementary food in pre-school children from rural communities

    Talavera, J. O., García-Vilchis, M. J., Labrada-Alba, T. S., Olvera-Flores, F., . . . Salgado-Enríquez, B. (2020). Moderate acute malnutrition prevention with a ready-to-use supplementary food in pre-school children from rural communities. Gaceta Medica De Mexico. 156(6), 499–508. doi:10.24875/GMM.M21000454

     

    Abstract:

    Introduction: Child malnutrition in Mexico reaches a prevalence as high as 27.5 % in rural areas. Objective: To assess the effectiveness of a ready-to-use supplementary food (RUSF) to correct mild acute malnutrition and prevent moderate acute malnutrition in preschool children from rural communities. Method: Randomized clinical trial, with assignment to two groups: group with RUSF (RUSF-g) or group without it (non-RUSF-g); children aged from two to five years, with weight-for-height Z-scores (WHZ) between -2 and -1 and low socioeconomic status were included. All received education on nutrition, health and hygiene twice monthly; the RUSF-g children had to consume one portion of the supplement every day. WHZ was assessed at baseline and at four, six, and 12 months. The comparison between groups was carried out with Cox proportional hazards model. Results: With regard to mild acute malnutrition correction in the RUSF-g, 68.7 versus 52.1 % in the control group was observed in the intent-to-treat analysis, with a hazard ratio (HR) = 1.25; in the per-protocol analysis of first semester, a HR = 1.48 was observed, and in the second semester, HR = 1.56. One patient progressed to moderate acute malnutrition. Conclusions: The RUSF-g showed a significantly higher resolution of mild acute malnutrition.

  • Nutritional profiles of juices

    Khomich, L. M., Ivanova, N. N., Berezhnaya, Yu. A., Shashin D. L., . . . Perova, I. B. (2020). Nutritional profiles of juices. Moscow: Planeta.

     

    Link to journal not available. If interested in requesting publication, please reach out to pepsiconutritionscience@pepsico.com

  • Opposing consumption trends for sugar-sweetened beverages and plain drinking water: Analyses of NHANES 2011–16 data

    Vieux, F., Maillot, M., Rehm, C. D., Barrios, P., & Drewnowski, A. (2020). Opposing consumption trends for sugar-sweetened beverages and plain drinking water: Analyses of NHANES 2011–16 data. Frontiers in Nutrition, 7, 587123. doi:10.3389/fnut.2020.587123

     

    Abstract:

    Background: Choosing water in place of sugar-sweetened beverages (SSB) can reduce added sugars while maintaining adequate hydration. The present goal was to examine 2011–16 time trends in SSB vs. water consumption across US population subgroups. Methods: Dietary intake data for 22,716 persons aged >4 years came from two 24-h dietary recalls in successive cycles of the National Health and Examination Survey (NHANES 2011–16). Water intakes (in mL/d) from plain water (tap and bottled) and from beverages (SSB and not-SSB) were the principal outcome variables. Intakes were analyzed by age group, income to poverty ratio (IPR), and race/ethnicity. Time trends by demographics were also examined. Results: SSB and water intakes followed distinct social gradients. Most SSB was consumed by Non-Hispanic Black and lower-income groups. Most tap water was consumed by Non-Hispanic White and higher-income groups. During 2011–16, water from SSB declined from 322 to 262 mL/d (p < 0.005), whereas plain water increased (1,011–1,144 mL/d) (p < 0.05). Groups aged <30 years reduced SSB consumption (p < 0.0001) but it was groups aged >30 years that increased drinking water (p < 0.001). Non-Hispanic White groups reduced SSB and increased tap water consumption. Non-Hispanic Black and lower income groups reduced SSB and increased bottled water, not tap. Conclusion: The opposing time trends in SSB and water consumption were not uniform across age groups or sociodemographic strata. Only the non-Hispanic White population reduced SSB and showed a corresponding increase in tap water. Lower-income and minority groups consumed relatively little plain drinking water from the tap.

  • Proceedings of a roundtable event ‘Is communicating the concept of nutrient density important?’

    Lockyer, S., Cade, J., Darmon, N., Flynn, M., . . . Buttriss, J. L. (2020). Proceedings of a roundtable event ‘Is communicating the concept of nutrient density important?’. Nutrition Bulletin, 45(1), 74-97. doi:10.1111/nbu.12421

     

    Abstract:

    The British Nutrition Foundation held a 1-day roundtable event to gather views from a wide range of stakeholders on the relevance and importance of the concept of nutrient density in supporting and motivating people to make healthier dietary choices. The opportunities and barriers associated with the use of this concept were also explored. The roundtable involved experts from research, public health nutrition, dietetics, retail and nutrition science communication, and this report describes the main themes emerging from the discussions. High obesity prevalence rates indicate that, on average, we are consuming too many calories relative to energy requirements; yet, the quality of our diets, with respect to certain vitamins and minerals and fibre, seems to be falling somewhat short of recommendations. Addressing this issue may require a more holistic approach than the current focus on restricting single nutrients prevalent in public health messaging internationally. Most members of the roundtable felt that communicating the concept of nutrient density may help in encouraging healthier food choices and dietary patterns that are higher in nutritional quality. However, while nutrient profiling has been used to guide front-of-pack labelling and in restricting the advertising of less healthy foods to children, there is a lack of consensus on the precise definition of a ‘nutrient dense’ food or which nutrients should be used as markers of the ‘healthiness’ of foods/drinks, and the term seems to be poorly understood by consumers and health professionals alike. Therefore, further work is required if tools around this concept are to be developed to try and successfully promote behaviour change.

  • Trends in tap and bottled water consumption among children and adults in the United States: Analyses of NHANES 2011-16 data

    Vieux, F., Maillot, M., Rehm, C. D., Barrios, P., & Drewnowski, A. (2020). Trends in tap and bottled water consumption among children and adults in the United States: Analyses of NHANES 2011-16 data. Nutrition Journal, 19, 10. doi:10.1186/s12937-020-0523-6

     

    Abstract:

    Background: Dietary Guidelines for Americans 2015–20 recommend choosing water in place of sugar-sweetened beverages (SSB). This study examined water consumption patterns and trends among children and adults in the US. Methods: Dietary intake data for 7453 children (4-18y) and 15,263 adults (>19y) came from two 24h dietary recalls in three cycles of the National Health and Nutrition Examination Survey (NHANES 2011–2016). Water was categorized as tap or bottled (plain). Other beverages were assigned to 15 categories. Water and other beverage intakes (in mL/d) were analyzed by sociodemographic variables and sourcing location. Consumption time trends from 2011 to 2016 were also examined. Total water intakes from water, other beverages and moisture from foods (mL/d) were compared to Dietary Reference Intakes (DRI) for water. Results: Total dietary water (2718mL/d) came from water (1066mL/d), other beverages (1036mL/d) and from food moisture (618mL/d). Whereas total water intakes remained stable, a significant decline in SSB from 2011 to 2016 was fully offset by an increase in the consumption of plain water. The main sources of water were tap at home (288mL/d), tap away from home (301mL/d), and bottled water from stores (339mL/d). Water and other beverage consumption patterns varied with age, incomes and race/ethnicity. Higher tap water consumption was associated with higher incomes, but bottled water was not. Non-Hispanic whites consumed most tap water (781mL/d) whereas Mexican Americans consumed most bottled water (605mL/d). Only about 40% of the NHANES sample on average followed US recommendations for adequate water intakes. Conclusion: The present results suggest that while total water intakes among children and adults have stayed constant, drinking water, tap and bottled, has been replacing SSB in the US diet.

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